Generic Name: – Sofosbuvir
Trade Name: – HEPCINAT 400mg – Manufactured By NATCO PHARMA LIMITED
Composition: – Each film coated tablet contains: Sofosbuvir equivalent to Sofosbuvir 400mg
Description: – Sofosbuvir 400mg tablet is an antiviral drug which is used in combination with other drugs for treatment of Hepatitis C Virus (HCV) infection. Compared to previous treatments, sofosbuvir based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduced duration of therapy.
Mechanism of action: – Sofosbuvir contains the oral nucleotide analogue of the hepatitis C polymerase inhibitor (HCV). The drug is an antiviral agent of direct action and directly affects the life cycle of HCV, inhibiting the replication of the virus. It can be incorporated into HCV RNA using NS5B polymerase and acts as a chain stopper. The drug is available for oral administration in the form of 400 mg tablets.
Dosage and administration : The recommended daily dosage of Sofosbuvir 400 mg tablets to be taken once a day with or without food. Sofosbuvir should be used in combination with ribavirin or in combination with pegylated interferon and ribavirin for the treatment of chronic hepatitis C (Chronic hepatitis C) in adults. It is highly advisable to prescribe the drug under strict medical supervision and advice.
Side Effects : –
Adverse events associated with the use of Sofosbuvir in combination with ribavirin may include, but are not limited to:
Adverse events associated with the use of Sofosbuvir in combination with Peginterferon Alfa and Ribavirin may include, but are not limited to:
Packing: – Each bottle contains 28 Sofosbuvir 400 mg tablets.
Storage: – Store at a temperature of 25 ° C in a dry place.
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